A Novel Clinico-anatomical Score Predicts Endovascular Failure in Patients With Chronic Limb-threatening Ischemia

This study assesses the infrainguinal successful endovascular treatment (iSET) score’s ability to predict risk of open revascularization in patients undergoing (ER) for chronic limb-threatening ischemia (CLTI). The iSET is a score between 1 and 63. It combines components Global Vascular Guidelines evidence-based as follows: = WIfI 2 + inflow disease 4 × GLASS FP 6 IP 3 IM pedal modifier was used retrospective analysis consecutive with CLTI January 2015 December 2018. Patients were stratified into low (0-21), moderate (22-42), high (43-63). primary outcome freedom from at years. included 159 limbs 150 12% (n 19), 53% 84), 35% 56) having low, moderate, scores respectively. Most presented tissue loss (86%), stage (64%), III (47%). more likely have received antibiotics prior ER (odds ratio [OR], 1.35; 95% confidence interval [CI], 1.08-1.70; P .013) less elective (OR, 0.36; CI, 0.18-0.72; .003). Kaplan-Meier survival curves showed that 2-year 100%, 93%, 79% iSET, respectively (Fig 1). Mortality, reinterventions, major amputations similar 30 days year (Table I). High predicted increased (hazard ratio, 4.75; 1.67-13.48; .003) cohort. novel comprehensive incorporating guideline-driven parameters. good prognostic tool predicting after ER. Further studies are needed validate it an adjunct managing CLTI.Table 1Thirty-day 1-year outcomes by groupsOverallLowModerateHighP-value30-day Death2 (3)03 (2)2 (1).775 Endovascular reintervention8 (11)08 (6)10 (5).447 Major amputation2 (2)02 (1)3 (1).848 Minor amputation13 (18)6 (1)8 (6)21 (11).0861-year Death11 (15)013 (9)11 (6).334 reintervention34 (48)31 (5)33 (24)37 (19).885 (18)014 (10)15 (8).262 amputation25 (36)6 (1)21 (15)38 (20).016Data percent (number). Open table new tab